Biomedical Engineering Reference
In-Depth Information
Even if the starring and scanning processes are tightly controlled, the data they produce may be
highly variable because of limitations of the microarray preparation process.
Figure 6-10
illustrates
several sources of variability associated with microarray preparation, including variations in relative
spot location (A), variations in spot density (B), variations in spot shape (C), and contamination (D).
Figure 6-10. Common Sources of Variability Associated with Microarray
Preparation. These sources of error affect both the spotting and starring
methods of microarray reading.
