Hardware Reference
In-Depth Information
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Dispensing
Mixing or dilution
Splitting
Type I
Type II
Type III
b
Backup droplets
Electrodes as storage cells
Fig. 2.6 ( a ) An example of a sequencing graph corresponding to a bioassay protocol; ( b )the
layout of a biochip with reserved area for error-recovery
All dispensing operations are scheduled for execution as early as possible and
their output droplets are stored on the biochip. We also dispense some droplets
as backup for possible error-recovery operations. After the bioassay is completed,
those unused backup droplets will be sent back to their corresponding reservoirs.
Thus, when an error occurs at a nonreversible operation, the control software
first checks whether the inputs of this operation can be provided by backup droplets
stored on the biochip. If the answer is yes, then the time cost for this operation can
be shortened. Otherwise, more operations will be executed during error-recovery.
Based on the above discussion, the operations in the bioassay can be divided into
three categories according to the number of operations and droplet consumptions in
their error-recovery processes, as shown in Fig. 2.6 a.
 
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