Risk management of chemicals and contaminated land – from planning to verification - Environmental Deterioration and Contamination: Problems and their Management - page 250

◦ biological effects;

◦ hazards to human health and the ecosystem;

- Manufacturing companies;

- Alternative and substitute chemical substances;

- Manufacturers;

- Alternative manufacturers, importers and suppliers;

- Alternative technologies, BAT (Best Available Technology) and the latest BREF

(Best Available Technology Reference Documents);

- Market alternatives;

- Emissions, release of chemicals into different environmental compartments and

phases;
◦ Exposure concentrations and levels at workplaces;

◦ Exposure concentrations and levels in the environment;

- Toxicity, carcinogenicity, reprotoxicity, endocrine disrupting and other adverse

effects;

- Environmental impacts at local, regional and global levels;

- Statistics on diseases and accidents;

- Costs of manufacturing and use;

- Methods to measure ERA, SEA and LCA.

A nonexhaustive list of the useful databases and other information sources on
the chemicals, their production, their adverse impacts on human health and environ-
ment as well as on the methods and technologies to manage the risk of chemicals is
provided below.
Information on chemicals , chemical properties, manufacturing companies, alter-
native and substitute substances. The existing chemical databases group and charac-
terize chemical substances from different points of view. Some generic and special lists
and databases are given here, their actual on-line availability can be found at the end
of the chapter:

- ACToR: US EPA Aggregated Computational Toxicology Resource;

- AGRITOX: Base de données sur les substances actives phytopharmaceutiques;

- ATSDR: Toxic Substances Portal;

- Australian Chemicals management;

- BEILSTEIN: Integrated searches for reaction and substance data (includ-

ing toxicity and environmental effects) with synthesis planning and chemical
sourcing;

- Biomolecule Binding Database: Database of measured binding affinities for

biomolecules;

- BPD: EU Biocidal Products Directive;

- CAS: Chemical Abstract Services;

- CCOHS: Canadian Centre for Occupational Health and Safety;

- CCOHS: CHEMINDEX;

- CCR: Canadian Categorization Results;

- CCRIS: Chemical Carcinogenesis Research Information System;

- ChEBI: Chemical entities of biological interest;