Chemistry Reference
In-Depth Information
Acknowledgements
The Lu group research described in this review has been supported by the Depart-
ment of Energy (DE-FG02-08ER64568) and the National Science Foundation
(CTS - 0120978, DMR - 0117792, and DMI - 0328162).
References
1.
Breaker , R.R. ; Joyce , G.F. ; A DNA enzyme that cleaves RNA ;
Chem. Biol.
, 1994 ,
1
( 4 ),
223 - 229 .
Ellington , A.D. ; Szostak , J . W . ;
In vitro
selection of RNA molecules that bind specifi c
ligands ;
Nature
, 1990 ,
346
( 6287 ), 818 - 822 .
Tuerk , C. ; Gold , L. ; Systematic evolution of ligands by exponential enrichment: RNA
ligands to bacteriophage T4 DNA polymerase;
Science
, 1990 ,
249
( 4968 ), 505 - 510 .
Beaudry , A.A. ; Joyce , G.F. ; Directed evolution of an RNA enzyme ;
Science
, 1992 ,
257
( 5070 ), 635 - 641 .
Bartel , D.P. ; Szostak , J.W. ; Isolation of new ribozymes from a large pool of random
sequences ;
Science
, 1993 ,
261
( 5127 ), 1411 - 1418 .
Breaker , R.R. ; DNA enzymes ;
Nat. Biotechnol.
, 1997 ,
15
( 5 ), 427 - 431 .
Sen , D. ; Geyer , C.R. ; DNA enzymes ;
Curr. Opin. Chem. Biol.
, 1998 ,
2
( 6 ), 680 - 687 .
Breaker , R.R.; Catalytic DNA: in training and seeking employment;
Nat. Biotechnol.
,
1999 ,
17
( 5 ), 422 - 423 .
Breaker , R.R. ; Making catalytic DNAs ;
Science
, 2000 ,
290
( 5499 ), 2095 - 2096 .
Breaker , R.R. ; Joyce , G.F. ; A DNA enzyme with Mg2+ -dependent RNA phosphoesterase
activity ;
Chem. Biol.
, 1995 ,
2
( 10 ), 655 - 660 .
Faulhammer , D. ; Famulok , M. ; Characterization and divalent metal -ion dependence of in
vitro selected deoxyribozymes which cleave DNA/RNA chimeric oligonucleotides;
J. Mol. Biol.
, 1997 ,
269
( 2 ), 188 - 202 .
Carmi , N. ; Shultz , L.A. ;
2.
3.
4.
5.
6.
7.
8.
9.
10.
11.
12.
Breaker , R.R. ;
In vitro
selection of self- cleaving DNAs ;
Chem.
Biol.
, 1996 ,
3
( 12 ), 1039 - 1046 .
Geyer , C.R. ; Sen , D. ; Evidence for the metal -cofactor independence of an RNA phos-
phodiester-cleaving DNA enzyme;
Chem. Biol.
, 1997 ,
4
( 8 ), 579 - 593 .
Roth , A. ; Breaker , R.R. ; An amino acid as a cofactor for a catalytic polynucleotide ;
Proc.
Natl. Acad. Sci. USA
, 1998 ,
95
( 11 ), 6027 - 6031 .
Santoro , S.W. ; Joyce , G.F. ; A general purpose RNA - cleaving DNA enzyme ;
Proc. Natl.
Acad. Sci. USA
, 1997 ,
94
( 9 ), 4262 - 4266 .
Liu , Z. ; Mei , S.H.J. ; Brennan , J.D. ; Li , Y. ; Assemblage of signaling DNA enzymes with
intriguing metal- ion specifi cities and pH dependences;
J. Am. Chem. Soc.
, 2003 ,
125
( 25 ),
7539 - 7545 .
Cuenoud , B. ; Szostak , J.W. ; A DNA metalloenzyme with DNA ligase activity ;
Nature
,
1995 ,
375
( 6532 ), 611 - 614 .
Li , Y. ; Breaker , R.R. ;
In vitro
selection of kinase and ligase deoxyribozymes;
Methods
,
2001 ,
23
( 2 ), 179 - 190 .
Coppins , R.L. ; Silverman , S.K. ; Rational modifi cation of a selection strategy leads to
deoxyribozymes that create native 3
13.
14.
15.
16.
17.
18.
19.
′
- 5
′
RNA linkages;
J. Am. Chem. Soc.
, 2004 ,
126
( 50 ),
16426 - 16432 .
Li , Y. ; Breaker , R.R. ; Phosphorylating DNA with DNA ;
Proc. Natl. Acad. Sci. USA
, 1999 ,
96
( 6 ), 2746 - 2751 .
Burmeister , J. ; von Kiedrowski , G. ; Ellington , A.D. ; Cofactor - assisted self - cleavage in
DNA libraries with a 3
20.
21.
′
- 5
′
- phosphoramidate bond ;
Angew. Chem. Int. Ed.
, 1997 ,
36
( 12 ),
1321 - 1324 .
