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categorically to be oxygen atoms of phosphate and, depending on pH, hydroxyl
groups on the ribose or deoxyribose moieties present. Further studies on the inter-
action of organotin(IV) complexes with calf thymus DNA revealed that no disrup-
tion of DNA double helix structure occurs. Neither does any DNA degradation
occur through oxidative stress mechanisms.
87
The question of how organotin com-
plexes may inhibit tumour growth remains, as yet, unanswered.
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