Chemistry Reference
In-Depth Information
95.
Phan , A.T. ; Kuryavyi , V. ; Patel , D.J. ; DNA architecture: from G to Z ;
Curr. Opin. Struct.
Biol.
, 2006 ,
16
( 3 ), 288 - 298 .
Neidle , S. ; Parkinson , G. ; Telomere maintenance as a target for anticancer drug discov-
ery ;
Nat. Rev. Drug Discov.
, 2002 ,
1
( 5 ), 383 - 393 .
Monchaud , D. ; Teulade - Fichou , M.P. ; A hitchhiker ' s guide to G - quadruplex ligands ;
Org.
Biomol. Chem.
, 2008 ,
6
( 4 ), 627 - 636 .
Shin - ya , K. ; Wierzba , K. ; Matsuo , K. ; Ohtani , T. ; Yamada , Y. ; Furihata , K.
et al.
; Telomes-
tatin, a novel telomerase inhibitor from Streptomyces anulatus;
J. Am. Chem. Soc.
, 2001 ,
123
( 6 ), 1262 - 1263 .
Kim , M.Y. ; Vankayalapati , H. ; Shin - Ya , K. ; Wierzba , K. ; Hurley , L.H. ; Telomestatin, a
potent telomerase inhibitor that interacts quite specifi cally with the human telomeric
intramolecular G- quadruplex ;
J. Am. Chem. Soc.
, 2002 ,
124
( 10 ), 2098 - 2099 .
Tauchi , T. ; Shin - ya , K. ; Sashida , G. ; Sumi , M. ; Okabe , S. ; Ohyashiki , J.H.
et al.
; Telomerase
inhibition with a novel G- quadruplex - interactive agent, telomestatin:
in vitro
and
in vivo
studies in acute leukemia;
Oncogene
, 2006 ,
25
( 42 ), 5719 - 5725 .
Gavathiotis , E. ; Heald , R.A. ; Stevens , M.F. ; Searle , M.S.
96.
97.
98.
99.
100.
101.
; Recognition and stabilization
of quadruplex DNA by a potent new telomerase inhibitor: NMR studies of the 2:1
complex of a pentacyclic methylacridinium cation with d(TTAGGGT);
Angew. Chem.
Int. Ed. Engl.
, 2001 ,
40
( 24 ), 4749 - 4751 .
Gavathiotis , E. ; Heald , R.A. ; Stevens , M.F. ; Searle , M.S. ; Drug recognition and stabilisa-
tion of the parallel-stranded DNA quadruplex d(TTAGGGT)4 containing the human
telomeric repeat;
J. Mol. Biol.
, 2003 ,
334
( 1 ), 25 - 36 .
Fedoroff , O.Y. ; Salazar , M. ; Han , H. ;
102.
103.
Chemeris , V.V. ; Kerwin , S.M. ; Hurley , L.H. ; NMR -
Based model of a telomerase- inhibiting compound bound to G - quadruplex DNA ;
Bio-
chemistry
, 1998 ,
37
( 36 ), 12367 - 12374 .
Haider , S.M. ; Parkinson , G.N. ; Neidle , S. ; Structure of a G - quadruplex - ligand complex ;
J. Mol. Biol.
; 2003 ,
326
( 1 ), 117 - 125 .
Clark , G.R. ; Pytel , P.D. ; Squire , C.J. ; Neidle , S. ; Structure of the fi rst parallel DNA
quadruplex - drug complex ;
J. Am. Chem. Soc.
, 2003 ,
125
( 14 ), 4066 - 4067 .
Cocco , M.J. ; Hanakahi , L.A. ; Huber , M.D. ; Maizels , N. ; Specifi c interactions of distamycin
with G- quadruplex DNA ;
Nucleic Acids Res.
, 2003 ,
31
( 11 ), 2944 - 2951 .
Reed , J.E. ; Arnal , A.A. ; Neidle , S. ; Vilar , R. ; Stabilization of G - quadruplex DNA and
inhibition of telomerase activity by square- planar nickel(II) complexes ;
J. Am. Chem.
Soc.
, 2006 ,
128
( 18 ), 5992 - 5993 .
Bertrand , H. ; Monchaud , D. ; De Cian , A. ; Guillot , R. ; Mergny , J.L. ; Teulade - Fichou ,
M.P.; The importance of metal geometry in the recognition of G-quadruplex-
DNA
104.
105.
106.
107.
108.
by
metal - terpyridine
complexes ;
Org. Biomol. Chem.
,
2007 ,
5
( 16 ),
2555 -
2559 .
Reed , J.E. ; Arnal , A.A. ; Neidle , S. ; Vilar , R. ; Stabilization of G - quadruplex DNA and
inhibition of telomerase activity by square- planar nickel(II) complexes ;
J. Am. Chem.
Soc.
, 2006 ,
128
( 18 ), 5992 - 5993 .
Dixon , I.M. ; Lopez , F. ; Tejera , A.M. ; Esteve , J.P. ; Blasco , M.A. ; Pratviel , G.
et al.
; A G -
quadruplex ligand with 10000-fold selectivity over duplex DNA;
J. Am. Chem. Soc.
, 2007 ,
129
( 6 ), 1502 - 1503 .
Evans , S.E. ; Mendez , M.A. ; Turner , K.B. ; Keating , L.R. ; Grimes , R.T. ; Melchoir , S.
et al.
;
End-stacking of copper cationic porphyrins on parallel- stranded guanine quadruplexes ;
J. Biol. Inorg. Chem.
, 2007 ,
12
( 8 ), 1235 - 1249 .
Keating , L.R. ; Szalai , V.A. ; Parallel - stranded guanine quadruplex interactions with a
copper cationic porphyrin;
Biochemistry
, 2004 ,
43
( 50 ), 15891 - 15900 .
Maraval , A. ; Franco , S. ; Vialas , C. ; Pratviel , G. ; Blasco , M.A. ; Meunier , B. ; Porphyrin -
aminoquinoline conjugates as telomerase inhibitors;
Org. Biomol. Chem.
, 2003
1
( 6 ),
921 - 927 .
Dixon , I.M. ; Lopez , F. ; Esteve , J.P. ; Tejera , A.M. ; Blasco , M.A. ; Pratviel , G.
et al.
; Porphy-
rin derivatives for telomere binding and telomerase inhibition;
Chembiochem.
, 2005 ,
6
( 1 ), 123 - 132 .
109.
110.
111.
112.
113.
114.