Chemistry Reference
In-Depth Information
117.
Malina , J. ; Kasparkova , J. ; Natile , G. ; Brabec , V. ; Recognition of major DNA adducts of
enantiomeric cisplatin analogs by HMG box proteins and nucleotide excision repair of
these adducts;
Chem. Biol.
, 2002 ,
9
, 629 - 638 .
Delalande , O. ; Malina , J. ; Brabec , V. ; Kozelka , J.; Chiral differentiation of DNA adducts
formed by enantiomeric analogues of antitumor cisplatin is sequence-dependent;
Biophys. J.
, 2005 ,
88
, 4159 - 4169 .
Reedijk , J. ; Improved understanding in platinum antitumour chemistry;
Chem. Commun.
,
1996 , 801 - 806 .
Farrell , N. ; Current status of structure -activity relationships of platinum anticancer
drugs: Activation of the
trans
geometry . In
Metal Ions in Biological Systems
, Vol.
32
,
Sigel , A. and Sigel, H.; Eds., Marcel Dekker, Inc., New York, Basel, Hong Kong, 1996 ,
603 - 639 .
Coluccia , M. ; Natile , G. ;
Trans
-platinum complexes in cancer therapy;
Anti - Cancer
Agents Med. Chem.
, 2007 ,
7
, 111 - 123 .
Kasparkova , J. ; Novakova , O. ; Marini , V. ; Najajreh , Y. ; Gibson , D. ; Perez , J. - M. ; Brabec ,
V. ; Activation of
trans
geometry in bifunctional mononuclear platinum complexes by a
piperidine ligand: Mechanistic studies on antitumor action;
J. Biol. Chem.
, 2003 ,
278
,
47516 - 47525 .
Marini , V. ; Christofi s , P. ; Novakova , O. ; Kasparkova , J. ; Farrell , N. ; Brabec , V. ; Conforma-
tion, protein recognition and repair of DNA interstrand and intrastrand cross- links of
antitumor
trans
- [PtCl
2
(NH
3
)(thiazole) ];
Nucleic Acids Res.
, 2005 ,
33
, 5819 - 5828 .
Coluccia , M. ; Nassii , F. ; Loseto , F. ; Boccarelli , A. ; Marigi รณ , M.A. ; Giordano , D. ; Intini ,
F.P. ; Caputo , P. ; Natile , G. ; A
trans
-platinum complex showing higher antitumor activity
than the cis congeners;
J. Med. Chem.
, 1993 ,
36
, 510 - 512 .
Brabec , V. ; Vrana , O. ; Novakova , O. ; Kleinwachter , V. ; Intini , F.P. ; Coluccia , M. ; Natile ,
G.; DNA adducts of antitumor
trans
- [PtCl
2
(E - imino ether)
2
];
Nucleic Acids Res.
, 1996 ,
24
, 336 - 341 .
Novakova , O. ; Kasparkova , J. ; Malina , J. ; Natile , G. ; Brabec , V. ; DNA - protein cross -
linking by
trans
- [PtCl
2
(E - iminoether)
2
]. A concept for activation of the
trans
geometry
in platinum antitumor complexes;
Nucleic Acids Res.
, 2003 ,
31
, 6450 - 6460 .
Farrell , N. ; Polynuclear platinum drugs . In
Metal Ions in Biological Systems
, Vol.
42
, Sigel ,
A. and Sigel , H. ; Eds., Marcel Dekker, Inc. , New York, Basel , 2004 , 251 - 296 .
Perego , P. ; Gatti , L. ; Caserini , C. ; Supino , R. ; Colangelo , D. ; Leone , R. ; Spinelli , S. ; Farrell ,
N. ; Zunino , F. ; The cellular basis of the effi cacy of the trinuclear platinum complex BBR
3464 against cisplatin- resistant cells ;
J. Inorg. Biochem.
, 1999 ,
77
, 59 - 64 .
Roberts , J.D. ; Beggiolin , G. ; Manzotti , C. ; Piazzoni , L. ; Farrell , N. ; Comparison of cyto-
toxicity and cellular accumulation of polynuclear platinum complexes in L1210 murine
leukemia cell lines;
J. Inorg. Biochem.
, 1999 ,
77
, 47 - 50 .
Farrell, N.; Polynuclear charged platinum compounds as a new class of anticancer agents:
Toward a new paradigm. In
Platinum - based Drugs in Cancer Therapy
, Kelland , L.R. and
Farrell , N.P. ; Eds., Humana Press Inc , Totowa, NJ , 2000 , 321 - 338 .
Brabec , V. ; Kasparkova , J. ; Vrana , O. ; Novakova , O. ; Cox , J.W. ; Qu , Y. ; Farrell , N. ; DNA
modifi cations by a novel bifunctional trinuclear platinum Phase I anticancer agent;
Biochemistry
, 1999 ,
38
, 6781 - 6790 .
Fink , D. ; Nebel , S. ; Aebi , S. ; Zheng , H. ; Cenni , B. ; Nehme , A. ; Christen , R.D. ; Howell ,
S.B.; The role of DNA mismatch repair in platinum drug resistance;
Cancer Res.
, 1996 ,
56
, 4881 - 4886 .
Aebi , S. ; Fink , D. ; Gordon , R. ; Kim , H.K. ; Zheng , H. ; Fink , J.L. ; Howell , S.B. ; Resistance
to cytotoxic drugs in DNA mismatch repair-defi cient cells;
Clin. Cancer Res.
, 1997 ,
3
,
1763 - 1767 .
Johnson , S.W. ; Ferry , K.V. ; Hamilton , T.C.; Recent insights into platinum drug resistance
in cancer;
Drug Resist. Updates
, 1998 ,
1
, 243 - 254 .
Drummond , J.T. ; Anthoney , A. ;
118.
119.
120.
121.
122.
123.
124.
125.
126.
127.
128.
129.
130.
131.
132.
133.
134.
135.
Modrich , P. ; Cisplatin and adriamycin resist-
ance are associated with MutL alpha and mismatch repair defi ciency in an ovarian tumor
cell line;
J. Biol. Chem.
, 1996 ,
271
, 19645 - 19648 .
Brown , R. ;