Biomedical Engineering Reference
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spherical casting mold. The pouch-like heart tissue had the structural
and contractile properties of a native myocardium. An implantation
study demonstrated that engineered grafts covering the surface of
whole hearts functionally communicated with the host myocardium
at two weeks after transplantation [6].
A
Biodegradable scaffold + cells
B
Polymer solution + cells
.PME
C
Decellularised whole heart + cells
D
Cell sheet
Scaffold or resected aorta
Figure 6d.1
Fabrication of organ-like structures using cultured
cardiomyocytes.
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