Biology Reference
In-Depth Information
In the previous example, we examined the effects of replicating a locus
in the source population, which changed the number of unique alleles
available in that source population. What if the number of unique alleles
is held constant, but the composition of the loci array differs between
two source populations? For example, in another simplistic comparison,
consider two source populations, each carrying a total of 100 unique alleles,
but differing as follows:
Source Population One with one locus with 100 unique alleles, each allele
at equal frequency of 0.01, the input code taking the following form:
<locus>
<dpdpoint x=“0.01” y=“0”/>
<dpdpoint x=“0.01” y=“1”/>
<dpdpoint x=“0.01” y=“2”/>...
the above lines being replicated, but with the y value changing from 3 to
96, and then fi nishing with the following:
<dpdpoint x=“0.01” y=“97”/>
<dpdpoint x=“0.01” y=“98”/>
<dpdpoint x=“0.01” y=“99”/>
</locus>
versus
Source Population Two with 50 loci, each with two unique alleles, one of
frequency 0.99 and one of frequency 0.01, with the following two input fi le
code statements describing two of these loci:
<locus><dpdpoint x=“0.99” y=“0”/><dpdpoint x=“0.01” y=“1”/>
</locus>
<locus><dpdpoint x=“0.99” y=“0”/><dpdpoint x=“0.01” y=“1”/>
</locus>
this pair of lines being repeated a total of 25 times in the input fi le for Source
Population Two.
In the following analyses, for each category of number of founders
selected from one or the other of these source populations, there were 25
trials, each with only one run. The means and ranges of these trials for each
level of number of founders are depicted in Fig. 7.11. When 100 individuals
(200 draws of alleles) are sampled, a mean of 87.2 unique alleles for source
population one versus 93.5 unique alleles for source population two are
retained in the founding population (a difference of approximately 7.3%; p
< 0.05). Note, however, that in source population one there are 100 “rare”
unique alleles (frequency = 0.01), while in source population two there are
50 common unique alleles (frequency = 0.95) and 50 “rare” unique alleles.
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