Biology Reference
In-Depth Information
11
10
B
B
B
B
B
9
B
B
B
8
7
6
5
B
4
B
B
3
2
B
A
A
A
A
A
A
A
A
A
1
1
10 100
FOUNDERS
Fig. 7.5
A comparison of how many founders need to be drawn from a source population
to be reasonably sure that all source unique alleles appear in the founding population. The
NEWGARDEN trials here are computed as in Fig. 7.1. Each A point is the average of one trial
(25 runs per trial, the indicated number of founders being drawn in each run) where there is
a total of two unique alleles of equal frequency in the source population (0.5). Each B point
is calculated in the same manner, except that the source population has a total of 10 unique
alleles, all of equal frequency (0.1). There were fi ve separate trials for each class of numbers of
founders drawn, and exactly overlapping trial averages appear as a single letter. As expected,
as the number of unique alleles at a locus increases in a source population, more founders will
be needed to ensure that all of the different alleles are captured among the founders.
1.2
B
1.0
B
B
B
B
B
0.8
B
B
B
B
B
B
0.6
B
B
B
0.4
B
B
B
B
B
B
0.2
B
B
0.0
B
B
B
B
B
1
10 100
FOUNDERS
Fig. 7.6
Standard deviation for the B trials outlined in Fig. 7.5. There is one locus with 10
alleles all of equal frequency (0.1) in the source population. When different numbers of
founders are randomly chosen, variance in the chance of obtaining all unique alleles drops
to approximately 0 when 40 or more founders (80 alleles) are chosen. Overlapping values are
depicted as a single letter.
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