Biomedical Engineering Reference
In-Depth Information
Fig. 9.10
The electrical conduction and landmarks of the heart system
nodes, which constitute the impulse propagation path. The impulse propagation time
and impulse propagation velocity for each pair of nodes vary due to different types
of muscles in the heart. To formalise the heart system, we define three constants im-
pulse propagation time
ConductionTime
, impulse propagation path
ConductionPath
and impulse propagation velocity
ConductionSpeed
. All these constants are initial
components, which are defined through a set of axioms (
axm
1-
axm
4).
To formalise the cardiac pacemaker, we define a set of constants (
LRL
,
URL
,
ARP
,
VRP
,
PVARP
, etc.), which expresses timing intervals. These timing intervals
are used as a set of configuration parameters. To model boolean behaviour of the
sensor and actuator, we define an enumerated set
status
. A set of axioms for the
cardiac pacemaker is defined in
axm
5 and
axm
6. All these constants and axioms
have been extracted from the technical specification [
7
], which are validated by the
cardiologist and the physiologist.
axm
1
:
partition(ConductionNode,
{
A
}
,
{
B
}
,
{
C
}
,
{
D
}
,
{
E
}
,
{
F
}
,
{
G
}
,
{
H
}
)
axm
2
:
ConductionTime
∈
ConductionNode
→ P
(
0
..
230
)
axm
3
:
ConductionPath
⊆
ConductionNode
×
ConductionNode
axm
4
:
ConductionSpeed
∈
ConductionPath
→ P
(
5
..
400
)
axm
5
:
LRL
∈
30
..
175
∧
URL
∈
50
..
175
∧
PVARP
∈
150
..
500
axm
6
:
ARP
∈
150
..
500
∧
VRP
∈
150
..
500
∧
status
={
ON, OFF
}
To define an abstract model of the closed-loop system, we develop the combined
model of the cardiac pacemaker and heart, where the cardiac pacemaker acts accord-
ing to the heart behaviour. The environment model of the heart behaves according
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