Biomedical Engineering Reference
In-Depth Information
Fig. 8.8 A two-dimensional
cellular automata model
In the usual case of CA realised on a D -dimensional grid, N consists of D -tuples
of indices from a coordinate set:
I D
I : N
The 2D cellular model therefore becomes
I 2
N
S | N |
T
:
S
To consider an automaton specified as a CA, let λ and α be the global state and
the global transition function of the CA, respectively. Then, λ ={ τ | τ : I 2
S }
and
α(λ(i,j)) = T(τ | N + (i, j )) for all τ in λ and (i, j) in I 2 .
Definition 3 (State transition of a cell) The heart muscle system is composed of
heterogeneous cells, the CA model of the muscle system, CAM CA , is characterised
by having no dependency on the type of cells. CAM CA is defined as follows:
CAM CA =
S,N,T
S
={
Active, Passive, Refractory
}
N
={
( 0 , 0 ), ( 1 , 0 ), (
1 , 0 ), ( 0 , 1 ), ( 0 ,
1 )
}
s m,n =
s m,n (t
+
1 )
s m,n =
T(s m,n ,s m + 1 ,n ,s m 1 ,n ,s m,n + 1 ,s m,n 1 )
where, s m,n denotes the state of the cell located at (m, n) and T is a transition func-
tion for CAM CA that specifies the next state, as shown in Fig. 8.9 .
Each cell in the heart muscle should be in one of the states Active , Passive or
Refractory . Initially, all cells are Passive . In this state, the cell is discharged elec-
trically and has no influence on its neighbouring cells. When an electrical impulse
propagates, the cell becomes charged and eventually activated ( Active state). The
cell then transmits an electrical impulse to its neighbour cells. The electrical im-
pulse is propagated to all the cells in the heart muscle. After activation, the cell
 
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