Biology Reference
In-Depth Information
Fig. 9. Petri net representation of the glycolysis metabolism of
Trypanosoma brucei
.
T
1
=
{
NADH, NAD
+
}
is simultaniously
a
P
-invariant, a trap and a siphon. In the absence of TPI
1
and TPI
2
,
t
2
=
{
DHAPg, DHAPc, GLY3Pg, GLY3Pc, Gly
}
is a trap.
If TPI
1
and TPI
2
act,
t
2
is not a trap any more, but
t
3
=
{
DHAPC, DHAPg, GLY3Pc, GLY3Pg, Gly, GA3P, BPGA, 3PGK,
2PGK, PEP, Pyr
}
forms a trap. We consider the case where the flux through
t
2
is positive and ALD is product-inhibited by
DHAPg.
