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Fig. 2. Processes of E-complex assembly as drafted before transfer into the Petri net model. Numbers at the edges refer to the column “ID” in the table of
reactions (Supplementary Table S1). The figure summarizes four different ways of E-complex assembly, described in literature and centering around donor and
acceptor splice cite recognition. Unbranched or unlabeled arrows represent an intermediate step for better visualization, without an explicitly given reaction.
Dashed arrows denote interactions within subcomplexes. Abbreviations: PTT = polypyrimidine track, 5'ss = donor splice site, 3'ss = acceptor splice site, BPS
= branchpoint sequence, 5term = 5' terminal exon. (Colours are visible in the online version of the article at www.iospress.nl . )
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