Biology Reference
In-Depth Information
Fig. 8. Some Petri nets are connected to a global place representing autoinducer (AI) in the environment*.
at this position if the 'alive' place contains tokens. The example shows a one-dimensional array, but
three-dimensional arrays are modeled in the same manner.
Further modeling methods for this kind of growth are mentioned in [Gronewold and Sonnenschein,
1998].
Figure 14 indicates a more detailed view in respect to cell growth and cell division. Once a new cell
has formed, the production of autoinducers is activated as a consequence of increasing cell density.
DISCUSSION
At present, the exploring, modeling and simulation of signaling networks is one of the most important
areas of bioinformatics and systems biology. Signal transduction, cellular rhythms and cell-to-cell com-
munication are three major subjects which have been intensely studied over the last decade. The area of
dynamic system modeling is increasingly being applied to biochemical problems like the aforementioned
*A colored version of the figure/chart is available at
In Silico Biol.
10
, 0003 <
http://www.bioinfo.de/isb/2010/10/0003/
>
, 1
February 2010.
