Chemistry Reference
In-Depth Information
O
O
Pd(dba)
2
,
TBAF.3H
2
O
+
Si
n
-C
5
H
11
Me
n
-C
5
H
11
I
2.329
2.330
2.331
n
-Pr
Me
Si
H
OH
n
-C
5
H
11
OH
Si
2.333
Me
n
-C
5
H
11
Me
n
-Pr
Me
n
-Pr
X
Si
Si
n
-C
5
H
11
O
n
-C
5
H
11
2.332
"ate" complex
X = F, OH
2.334
Scheme 2.105
Pd(0), base
SiMe
2
OH
Ar
Ar
+
Ar'
Br
Ar'
2.335
L
2
Pd(0)
Ar
Ar
Br
Ar'
reductive
elimination
oxidative
a
dditon
SiMe
2
OH
Ar'
2.335
Ar
Ar
L
2
Pd
base
L
2
Pd
2
.
2
6
Br
Ar'
O
Me
Si
Me
Ar'
2.337
Ar
ligand exchange
L
2
Pd
Me
Si
O
Br
(Me
2
SiO)
n
Ar'
intramolecular
transmetallation
Me
2.338
Scheme 2.106
I OTHP
NaH, Pd
2
(dba)
3.
CHCl
3
SiMe
2
OH
BnMe
2
Si
OTHP
BnMe
2
Si
2.340
2.341
I
EtO
2
C
Pd(dba)
2
, TBAF
EtO
2
C
OTHP
2.342
Scheme 2.107
