Chemistry Reference
In-Depth Information
t
-Boc
t
-Boc
N
N
SiMe
3
Me
Me
I
I
1. DIAD, Ph
3
P
2. K
2
CO
3
, MeOH
+
OH
O
HO
H
OMe
OMe
8.420
8.421
8.422
t
-Boc
t
-Boc
N
N
OH
Me
Me
1. 9-BBN; NaOH, H
2
O
2
2. Pd(OAc)
2
, dppp, Ag
2
CO
3
I
Grubbs I
O
O
H
H
OMe
OMe
8.423
8.424
Me
N
1. SeO
2
, NaH
2
PO
4
2. MsCl, Et
3
N
3. CF
3
CO
2
H, then NaHCO
3
O
H
OMe
8.425
Scheme 8.114
[Ru]
[Ru]
[Ru]
Scheme 8.115
R
1
O
O
O
Grubbs
I
I
Grubbs II
R
1
= H;
R
2
= Me
R
1
= Me;
R
2
= H
NC
NC
NC
R
2
8
.
6
8
.
4
2
7
8
.
4
8
Scheme 8.116
