Chemistry Reference
In-Depth Information
Tab l e 8 . 2
Cross-metathesis reactivities
type 1: fast self-metathesis
type II: slow self-metathesis
(R = alkyl, Ph)
(Z = CO
2
R, CO
2
H,
CHO, COR)
HO
R
Z
HO
O
HO
X
2
B
R
3
Si
PG
O
HN
(RO)
2
P
F
2n+1
C
n
R
type III: no self-metathesis
type IV: inactive - mere spectators
R
R
PGO
O
2
N
R
R
R
PGO
PhSO
2
OH
OH
Grubbs I
I
OAc
OAc
type II
type I
8.318
slow
OH
self-metathesis
OH
Grubbs II
secondary-
metathesis
OH
AcO
OAc
8.317
Scheme 8.88
Grubbs I
I
CO
2
Et
CO
2
Et
R
8.319
8.320
R = H, Me
8.321
E
:
Z
= 2:1
Scheme 8.89
