Biomedical Engineering Reference
In-Depth Information
4
3
5
2
3
14
5
10
12
5
14
3
7
7
6
14
7
24
1
24
25
3
22
1
6
14
7
15
17 18 20
7
8
13
13
6 14
21
19
9
10 11
3
8
4
9
12 11 16
4
2
23
21
3
14
5
6
14
3
Figure 3.35
Broadcast addressing for the multiplexed assay chip.
In Figure 3.35, the number of control pins is reduced from 59 to 25, almost
a 60% reduction compared to the direct-addressing method. Due to consider-
able reduction in wiring complexity, fabrication cost is reduced significantly.
There is no increase in the assay time compared to a direct-addressing chip
that uses 59 electrodes.
The cross-reference-based method also leads to a significant reduction in
the number of control pins, but at the expense of higher assay completion
times. The results are shown in Figure 3.36. With broadcast addressing,
we obtain an assay completion time of 73 s. The cross-referencing-based
method requires 30 control pins but a longer completion time of 132 s. The
Cross-referencing-
based method
140
120
Broadcast
addressing
method
100
Array-partitioning-
based method
80
60
40
20
0
Figure 3.36
Comparison of assay-completion time.
