Spectroscopy and Molecular Changes in Cancer Cells - Vibrational Spectroscopy for Tissue Analysis - page 29

The information presented in this chapter covers the changes that take
place at the molecular level in cancer cells and can be detected using the spec-
troscopic techniques described. It is important to understand the biology and
chemistry of cancer cells, which will help in analysing chemical structural
properties of the cancer cells by spectroscopic means. A good knowledge of
cell structure will allow to us to predict and follow the chemical pathway by
which the disease progresses.
References
1. Stone, N., Kendell, C., Shepherd, N., Crow, P. and Barr, H. 2002. Near-infrared
Raman spectroscopy for the classification of epithelial pre-cancers and cancers.
J. Raman Spectrosc . 33, 564-573.
2. Stone, N., Kendall, C., Smith, J., Crow, P. and Barr, H. 2004. Raman spectroscopy
for identification of epithelial cancers. Faraday Discussion 126, 141-157.
3. Franks, L. M. 1991. Introduction to the Cellular and Molecular Biology of Cancer .
New York: Oxford University Press.
4. LaFond, R. E. 1988. Cancer: The Outlaw Cell , 2 nd ed. Washington, DC: American
Chemical Society.
5. Lodish H., Berk A., Zipursky S. L., Matsudaira P., Baltimore D., and Darnell J. E.
2000. Molecular Cell Biology , 4 th ed. New York: W. H. Freeman & Co.
6. King, R. J. B., and Benjamin R. J. 2006. Cancer Biology , 3 rd ed. New York: Pearson/
Prentice Hall.
7. Dukor, R. K. 2002. Vibrational spectroscopy in the detection of cancer, Biomedical
Applications , 3335-3359.
8. Cooper, G. M., 2003. The Cell: A Molecular Approach , 3 rd ed. Sunderland, MA:
Sinauer Associates.
9. Gortan Kumar, Robbins. 1999. Pathologic Basis of Disease . Philadelphia: Saunders.
10. Huang, Z., McWilliams, A., Lui, M., McLean, D. I., Lam, S., and Zeng, H. 2003.
Near-infrared Raman spectroscopy for optical diagnosis of lung cancer. Int. J.
Cancer 107, 1047-1052.
11. Huang, Z., Lui, H., McLean, D. I., Korbelik, M., and Zeng, H. 2005. Raman
spectroscopy in combination with background near-infrared autofluorescence
enhances the in vivo assessment of malignant tissues. Photochem. Photobiol. 81,
1219-1226.
12. Austrian Centre for Electron Microscopy and Nanoanalysis. 2010. Infrared and
Raman microspectrometry, Graz, Austrian Centre for Electron Microscopy and
Nanoanalysis, http://www.felmi-zfe.tugraz.at/ (accessed on December 10, 2011).
13. Skala, M. C., Palmer, G. M., and Vrotsos, K. M. 2007. Comparison of a physical
model and principal component analysis for the diagnosis of epithelial neoplasias
in vivo using diffuse reflectance spectroscopy. Optics Express 15(12), 7863-7875.
14. Kneipp, K., Kneipp, H., Kartha, V. B., Manoharan, R., Deinum, G., Itzkan, I.,
Dasari, R. R., and Feld, M. S. 1998. Detection and identification of a single DNA
base molecule using surface-enhanced Raman scattering (SERS). Phys. Rev.
E57(6), 6281-6284.