hERG Potassium Channels in Drug Discovery and Development - Ion Channels and Their Inhibitors - page 168

Table 2 (continued)
Drug Structure Year of FDA approval Year of FDA withdrawal Medical

indication

Astemizole 1988 1999 Allergic rhinitis F

N

N

N

N

O

Terfenadine

1985 1998 Allergic rhinitis

HO

OH

N

Grepafloxacin 1997 1999 Bacterial

infection

O

F

O

N

OH

N

N