hERG Potassium Channels in Drug Discovery and Development - Ion Channels and Their Inhibitors - page 165

FDA and medical indication
Drug Structure Year of FDA approval Year of FDA withdrawal Medical

indication

Amiodarone 1985 2006 Cardiac

arrhythmia

O

I

N

O

I

O

Bepridil 2005 2007 Angina pectoris

N

O N

Mibefradil 1997 1998 Hypertension and

angina
pectoris

F

N

N

N

O

O

O