Biomedical Engineering Reference
In-Depth Information
NaYF
4
: Yb
3+
/Er
3+
@nSiO
2
@CTAB/mSiO
2
NaYF
4
: Yb
3+
/Er
3+
@nSiO
2
(a)
NaYF
4
: Yb
3+
/Er
3+
TEOS
TEOS
CTAB
Drug molecule
Drug
loading
Drug
release
Drug-NaYF
4
: Yb
3+
/Er
3+
@nSiO
2
@mSiO
2
NaYF
4
: Yb
3+
/Er
3+
@nSiO
2
@mSiO
2
NaYF
4
: Yb
3+
/Er
3+
@nSiO
2
@mSiO
2
(b)
(d)
2000
1600
1200
50 nm
(c)
800
400
0
20
40
Cumulative Released IBU (%)
60
80
100
20 nm
FIGURE 3.10
(a) Schematic for the experimental process for core-shell structured NaYF
4
:Y b
3+
/Er
3+
@
nSiO
2
@mSiO
2
nanospheres and subsequent loading and release of IBU. (b-c) TEM images
of NaY F
4
:Y b
3+
/Er
3+
@nSiO
2
@mSiO
2
nanospheres. (d) Up-conversion emission intensity of
Er
3+
in IBU- NaYF
4
:Y b
3+
/Er
3+
@nSiO
2
@mSiO
2
as a function of the cumulatively released IBU.
(Reprinted with permission from Kang X., Cheng Z., Li C., et al.,
J. Phys. Chem. C
115: 15801-
15811, Copyright 2011, American Chemical Society.)
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