Functional Mesoporous Silica Nanoparticles with a Core-Shell Structure for Controllable Drug Delivery - Advanced Bioactive Inorganic Materials for Bone Regeneration and Drug Delivery - page 51

(a)

TEOS Calcination

Si

Si
Si

(b)

(d)

(a)

PVP

(c)

CTAB

(b) (c)

200 nm

(d) (e)

100 nm

50 nm

FIGURE 3.1
(a) Schematic drawing of the formation process of HMS nanoparticles. (b) SEM image of
HMS nanoparticles. (c) TEM image of the as-synthesized HMS nanoparticles. (d) TEM and (e)
HRTEM images of the calcined HMS nanoparticles. (Reprinted from Zhu Y., Shi J., Chen H., et
al., Micropor. Mesopor. Mater . 84: 218-222, 2005, with permission from Elsevier Ltd.)