Biomedical Engineering Reference
In-Depth Information
6
Preparation and Mechanism of
Novel Bioceramics with Controllable
Morphology
and Crystal Growth
Kaili Lin and Jiang Chang
CONTENTS
6.1 Introduction ................................................................................................ 147
6.2 Preparation and Mechanism of Novel Bioceramics with
Controllable Morphologies and Crystal Growth .................................. 148
6.2.1 Crystal Growth and Morphology Control of Bioceramic
Particles ........................................................................................... 148
6.2.2 Fabrication and Morphology Control of the Nanostructured
Bioceramics with Novel 3D Architectures ................................. 157
6.2.3 Morphology Control of the Bioceramics with Oriented
Structures Similar to Bone and Tooth ......................................... 165
6.3 Conclusion and Perspective ..................................................................... 168
References ............................................................................................................. 169
6.1 Introduction
The ceramics used for repair and reconstruction of diseased or damaged
parts of the muscular-skeletal system are termed as bioceramics (Hench
1991). The bioceramics can be classified into bioinert, resorbable, and bioac-
tive ceramic materials. They can be used in dense, porous, granules, particles,
and coatings, and also used as the component for composites. The materials
based on calcium phosphate (Ca-P), such as hydroxyapatite [Ca
10
(PO
4
)
6
(OH)
2
,
HAp], β-tricalcium phosphate [β-Ca
3
(PO
4
)
2
, β-TCP], octacalcium phosphate
[Ca
8
H
2
(PO
4
)
6
·5H
2
O, OCP], and calcium phosphate cement (CPC) are widely
used in biomedical fields due to their excellent biocompatibility, osteoconduc-
tive properties, and similarity to the inorganic component of human beings
(Lin et al. 2012). In recent decades, another kind of bioceramics, materials
based on calcium silicate (Ca-Si), such as bioglass, glass-ceramics, and cal-
cium silicate ceramics, are developed due to their bioactivity and biodegrad-
ability. The bioceramics can be also used as a drug or gene delivery system.
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