The Choice of Suitable Online Analytical Techniques and Data Processing for Monitoring of Bioprocesses - Measurement, Monitoring, Modelling, and Control of Bioprocesses - page 261

Table 2 (continued)

Device Application Settings and data pre-processing Cell

density

References

Aber 214 M E. coli HMS174 (DE3) expressing

viral autoprotease fusion protein

Dual frequency at 0.5 MHz, high range, low-pass
filter at 1 s;
Raw data with Savitzky-Golay over 25 data
points

0-40 g/L [ 56 ]

BM220 Aber instruments, 1.12 MHz
and background compensation at
15.65 MHz

E. coli JM 105pUC19-GFP, E. coli
BL21 star (DE3) p6xHis-GFP,
E. coli K12DH5alpha pTRCHIS
T-Saphire

1.12 MHz and background compensation at
15.65 MHz

70 g/L [ 57 ]

Aber BM 210 A. adeninivorans LS3 25 logarithmically increasing frequencies from 0.1

to 19.49 MHz;
Combination of moving-point average and
Savitzky-Golay, Cole-Cole with Leuvenberg-
Marquart

0-20 g/L [ 58 , 59 ]

Aber 220 S. cerevisiae, S. cerevisiae T65 Frequency spectra from 100 kHz to 500 MHz

acquired; Multifrequency mode 0.1-10 MHz

0-120 g/
L

[ 60 , 61 ]

Aber BM 210 S. cerevisiae, K. marxianus For each run, 25 frequencies from 0.1 to 20 MHz

were scanned every 15 s;
81-point (20 min) moving point average and
Savitzky-Golay smoothening on top, linear
prediction model

0-10 g/L [ 62 ]

Aber BM 210 S. cerevisiae, K. marxianus,

C. utilis, P. pastoris

Dual-frequency measurements at 500 kHz and
10 MHz, low-pass filter at 60 s, data
acquisition every 20 s;
Moving-point average over routine interval of
2 min, linear prediction model

0-8 g/L [ 63 , 64 ]

Fogale biosystem S. cerevisiae 0.3-10 MHz;

Cole-Cole with constrained Leuvenberg-
Marquart

- [ 65 ]