Biomedical Engineering Reference
In-Depth Information
TABLE 8.1
PEM Coatings on Materials for Different Tissue Engineering Applications
Application
Substrate
Film
Cells
MainFindings
Reference
Bone
Ti
(PLL/DNA)
(PAH/DNA)
Osteoblasts
- Deposition of calcium phosphate was enhanced on
DNA coatings
- Formation of carbonate apatite
- Simulated body luids pretreated ilms increased the
deposition of osteocalcin
van den
Beucken et al.
2007a, 2007b
Ti
CHI/gelatine
Osteoblasts
- Increased viability and proliferation
Cai et al. 2005
Ti
CHI/HA ilms
+ RGD X-linked
at the surface
Osteoblasts
Staphylococcus
aureus
- No adhesion for native CHI/HA ilm, enhanced
adhesion in the presence of the peptide for CHI ending
surface only
- A decreased adhesion and enhance antibacterial
activity of CHI/HA ilms (w or w/o RGD)
Chua et al. 2008
Electrospun PCL ibers
Gelatin/PSS
coated with
bonelike
calcium
phosphate
Osteoblasts
- Enhancement of cytocompatibility
- Increased proliferation
Li et al. 2008
PLA nanoibrous
scaffold
PDDA/gelatine
Osteoprogenitors
- Change in surface wettability
- Increase adhesion and proliferation
Liu et al. 2005b
Bone Marrow
PLA scaffold
PEI/GEL
Chondrocytes
- Increased adhesion and growth
Zhu et al. 2004
PDMS (μluidic
channels)
(PDDA/clay)/
(COL/FN)
Murine bone
marrow cells
- Automated microluidic perfusion system
- Increased cell attachment and spreading
Mehta et al.
2007
PA hydrogel ICC
scaffolds
PDDA/Clay
platelets
Hematopoietic
stem cells
- Expansion of CD34+ stem cells and B-lymphocyte
differentiation
Nichols et al.
2009
Vascular
engineering
PET ilaments, thread
and prostheses
(PSS/PAH)
(PLL/PGA)
(PLL/HA)
-
- Characterization of ilm deposition
- Good mechanical stability of the ilms under stretching
Rinckenbach et
al. 2007
PCL
-CHI-CL-
gPEG/HEP
Platelets
- New derivative of CHI: chitosan-g-PCL-b-PEG
- Increased in plasma recalciication time for the coating
Liu et al. 2007
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