Bioceramic Coating on Titanium by Physical and Chemical Vapor Deposition - Biological and Biomedical Coatings: Processing and Characterization - page 322

6

: Noncoated
: ACP
: OAp (heat-treated)
: HAp disk

5

4

3

2

1

0

2 days 4 days 8 days

FIGURE 7.31
ALP activity of SaOS-2 cells on noncoated, ACP- and OAp-coated blasted Ti-6Al-4V plates and HAp disk 2,
4, and 8 days after they were cultured. OAp coatings were heat-treated in a silica ampoule at 873 K for 7.2 ks.
(B-L × 16.7 = U/l, 310 K).

Many studies on in vivo evaluation of Ti implants with calcium phosphate coatings by
PVD have been reported. (33,38,80-85) The improvement in the bone compatibility of the Ti
implants has been demonstrated by evaluating the removal torque, (38,80) ultimate interfa-
cial strength (81) and bone-implant contact (BIC) (33,48,80-82) in animals. The values of removal
torque of noncoated and ACP-coated blasted Ti-6Al-4V alloy implants from the femurs of
Japanese white rabbits are shown in Figure 7.32. (38) The removal torque increased with the
duration of implantation, and the values for the ACP-coated implants were greater than
those of noncoated implants. It was statistically improved by the ACP coating 2 weeks

0.6

: Noncoated
: ACP-coated

0.5

0.4

*

0.3

0.2

0.1

0

2 weeks 4 weeks

FIGURE 7.32
Removal torque values of noncoated and ACP-coated blasted Ti-6Al-4V alloy implants 2 and 4 weeks after
implantation in femurs of Japanese white rabbits (* p < 0.05).