Biomedical Engineering Reference
In-Depth Information
4
ThermalSprayedBioceramicCoatings:
NanostructuredHydroxyapatite(HA)
and
HA-B
asedComposites
HuaLi
CONTENTS
Background and Current Problems.......................................................................................... 138
Principle of Thermal Spray........................................................................................................ 142
Synthesis of HA Powder for Coating Deposition................................................................... 145
Properties of HA ..................................................................................................................... 145
Synthesis and Fabrication of HA Powder........................................................................... 145
HA-Based Composite Powder ............................................................................................. 148
Nanostructured HA-Based Bioceramic Coatings Deposited by Thermal Spray ............... 148
Mechanical Properties and Relationship between Nanostructure and Properties............ 167
Nanostructured HA-Based Composite Coatings ................................................................... 171
Co-/Postspray Treatment of HA Coatings .............................................................................. 178
Influence of HA Feedstock.................................................................................................... 178
Biocompatibility Evaluation of the Nanostructured Bioceramic Coatings by In Vitro
Cell Culture .................................................................................................................................. 185
References..................................................................................................................................... 190
The predominant purpose of biomedical materials is to produce a part or facilitate a func-
tion of the human body in a safe, reliable, economical, and physiologically acceptable man-
ner. A prerequisite for any synthetic material implanted in the body is that it should be
biocompatible in the sense of not producing an inflammatory tissue reaction. In addition,
the implanted material is expected to withstand applied physiological forces without sub-
stantial dimensional changes, catastrophic brittle fracture, or fracture in the long term
from creep, fatigue, or stress corrosion. Accordingly, thermal sprayed bioceramic coatings,
which have been extensively proposed as implants for bone and joint replacements, must
possess acceptable biocompatibility and sufficient mechanical performances. This chapter
addresses the fundamentals of coating deposition of the bioceramics, typically hydroxy-
apatite (HA) and HA-based composites, apart from other related issues, such as fabrication
of nanostructured feedstock, characterization of the nanostructures inside the coatings
and their influence on coating properties, effect of the nanostructures and phase composi-
tions on behaviors of the osteoblast cells cultured on the biomedical coatings, co-/post-
spray treatment of the coatings, and so forth. The biomaterials-cells interactions control
Search WWH ::
Custom Search