Biomedical Engineering Reference
In-Depth Information
nopyranosyl hydroxyphosphinyl)-l-leucyl-l-tryptophane, Phos-
phoramidon); 3,4-dichloroisocoumarine (1 - 43); EGTA (200 - 500);
hirudin (150- 200 ATU); phosphoamidon (4 - 330), tissue inhibitor
of metalloproteinase 2 (10; TIMP-2); trypsin inhibitor (from chicken
egg white or soy bean; 10 - 100).
References
Zöllner H(1992) Handbook of enzyme inhibitors, 2nd ed. VCH, New York
8.6 Single-Letter Codes and Molecular Masses
of Amino Acids
The single-letter code is helpful to describe longer amino acid
sequences. It is derived from the three-letter code of amino acids
(aa).
Checking number CN and reference number AA is used for
unequivocal characterization of each amino acid sequence:
NR
=
CN
AA
i
·
i
=
i
1
Sequence (IUPAC-IUB): His-Glu-Leu-Pro-Met-Ala-Thr-His-Glu
Example
Single-letter code: HELPMATHE
CN:
=
441
1
·
9+2
·
7+3
·
11+4
·
15+5
·
13+6
·
1+7
·
17+8
·
9+9
·
7
NR:
9
M
r
:
1064.19
COMP:
A
1
R
0
N
0
D
0
C
0
Q
0
E
2
G
0
H
2
I
0
L
1
K
0
M
1
F
0
P
1
S
0
T
1
W
0
Y
0
V
0
CN: checking number; AA: reference number (cf. Table 8.13); i:
position number of the respective aa within the sequence (i of the
N-terminal aa is 1); NR: total number of aa within the polypeptide
chain; M
r
: molar mass of the polypeptide; COMP: true formula
of the polypeptide (all naturally occurring aa have to be listed, aa
which are no part of the chain are indicated by “0”).
References
Bairoch A (1982) Biochem J 203:527
