Biomedical Engineering Reference
In-Depth Information
Further Reading
Alberts, B., Bray, D., Johnson, A., Lewis, I., Raff, M., Roberts, K., and Walter, P., 1998. Essential Cell Biology: An
Introduction to the Molecular Biology of the Cell, Garland Publ., Inc., New York.
Beckmann, J., Scheitza, S., Wernet, P., Fischer, J.C., Giebel, B., 2007. “Asymmetric cell division within the human
hematopoietic stem and progenitor cell compartment: identification of asymmetrically segregating proteins”.
Blood 109 (12): 5494-501. http://dx.doi.org/10.1182/blood-2006-11-055921 . PMID 17332245.
Black, J.G., 1996. Microbiology: Principles and Applications, third ed. Prentice Hall, Upper Saddle River, NJ.
Dence, C.W., and Lin, S.Y., 1992. Introduction. In Dence, C.W., and Lin, S.Y. (Eds.), Methods in Lignin Chemistry.
Berlin Heidelberg: Springer-Verlag.
Fengel, D., and Wegener, G., 1989. Wood Chemistry, Ultrastructure, Reactions. Walter deGruyter, Berlin.
Moran, L.A., Scrimgeourh, K.G., Horton, R., Ochs, R.S., and Rawn, J.D., 1994. Biochemistry, Second ed. Prentice Hall,
Upper Saddle River, NJ.
Shuler, M.L. and F. Kargi., 2006. Bioprocess Engineering - Basic Concepts, Second ed. Prentice Hall, Upper Saddle
River, NJ.
Sj¨str¨m, E., 1993. Wood Chemistry - Fundamentals and Applications, Second ed., Academic Press, San Diego, CA.
Song, X., Zhu, C., Doan, C., Xie, T., 2002. “Germline stem cells anchored by adherens junctions in the Drosophila
ovary niches”. Science 296 (5574): 1855-7. doi:10.1126.
Takahashi, K., Yamanaka, S., 2006. "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast
cultures by defined factors". Cell 126 (4): 663-76. http://dx.doi.org/10.1016/j.cell.2006.07.024 . PMID 16904174.
Vierbuchen, T., Ostermeier, A., Pang, Z.P., Kokubu, Y., S ¨ dhof, T.C., Wernig, M., 2010-02-25. “Direct conversion of
fibroblasts to functional neurons by defined factors”. Nature 463 (7284): 1035-41. doi:10.1038/nature08797. PMC
2829121. PMID 20107439.
PROBLEMS
2.1. What makes a living cell?
2.2. Briefly compare prokaryotes with eukaryotes in terms of internal structure and
functions.
2.3. What is a virus cell? What is a prion?
2.4. What are the major classes of fungi? Cite the differences among these classes briefly.
2.5. What are the major classes of algae? Cite the differences among these classes and their
potential applications.
2.6. Briefly describe distinct features of actinomycetes and their important products.
2.7. Briefly compare protozoa with algae in terms of their cellular structures and functions.
2.8. What is a stem cell?
2.9. What are major
sources of carbon, nitrogen, and phosphorus
in industrial
fermentations?
2.10. Explain the functions of the following trace elements in microbial metabolism: Fe, Zn,
Cu, Co, Ni, Mn, vitamins.
2.11. What are chelating agents? Explain their function with an example.
2.12. Cite five major biological functions of proteins.
2.13. Briefly describe the primary, secondary, tertiary, and quaternary structure of proteins.
What could happen if you substituted a tyrosine for a cysteine in the active site? What
might happen if the substitution occurred elsewhere?
2.14. Contrast DNA and RNA. Cite at least four differences.
2.15. Why are phosphates being added in a fermentation medium?
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