Sustainability and Stability - Bioprocess Engineering: Kinetics, Biosystems, Sustainability and Reactor Design - page 851

(a) Perform a steady-state mole balance on B.
(b) Plot the mole balance equation on the Fig. P16.1 .
(c) Determine the possible steady-state conversion or conversions in the effluent
stream.
(d) Comment on the stability of the solution or solutions obtained in part c).
16.2. A cell culture grows on a glucose media is inhibited by the substrate under isothermal
conditions and the growth rate is governed

m max S
K S þSþS 2

m G ¼

= K I

m max ¼ 0.1 h 1 , K S ¼ 0.1 g/L, and K I ¼ 10 g/L. The cells have a specific death rate
of k d ¼ 0.005 h 1 and a yield factor of YF X/S ¼ 0.75. The culture is to be grown in a
chemostat with a sterile feed containing S 0 ¼ 80 g/L substrate and a dilution rate of
D ¼ 0.06 h 1 . Determine
(a) The steady-state solutions;
(b) Which steady-state solutions in a) can be operated, and which one is desired, and
why?
(c) How should you start the reactor if the desired operating conditions are to be met?
16.3. A cell culture grows on a glucose media is inhibited by the substrate under isothermal
conditions and the growth rate is governed

with

m max S
K S þSþS 2

m G ¼ (P16.2-1)

= K I

m max ¼ 0.8/h, K S ¼ 0.1 g/L, K I ¼ 10 g/L. The cells has a specific death rate of
k d ¼ 0.01 h 1 and a yield factor of YF X/S ¼ 0.6. The culture is to be grown in a chemo-
stat with a sterile feed containing S 0 ¼ 80 g/L substrate and a dilution rate of
D ¼ 0.6 h 1 . Determine
(a) The steady-state solutions;
(b) Which steady-state solutions in a) can be operated, and which one is desired, and
why?
(c) How should you start the reactor if the desired operating conditions are to be
met?
16.4. A first-order homogeneous liquid reaction is carried out in a CSTR. The reactor
initially contains 18 L of reactant (A) with a concentration of 3 mol/L. The initial
temperature is 373 K and the reactor is well-insulated so that it can be assumed to be
adiabatic. The feed rate is at 60 cm 3 /s. The density of the liquid is 1000 kg/m 3 and the
heat capacity is 4.182 kJ/(kg $ K). D H R ¼ 2.09 10 5 J/mol-A. Feed concentration is
3 mol/L. The reaction rate is given by

with

= L$s

r A ¼ 4:4810 6 C A exp ð7554= TÞ mol

(a) Determine whether MSS exist.
(b) Construct the ignition e extinction curve for the system.