Biomedical Engineering Reference
In-Depth Information
O
O
HO
P
OH
HO
P
OH
O
O
HO
O
+ H
2
O
P
+ H
3
PO
4
O
HO
P
O
NH
2
N
O
HO
O
P
NH
2
N
5
N
O
O
N
N
N
5
4
1
O
N
3
2
N
4
1
3
2
HO
OH
HO
OH
FIGURE 10.17
Structure of ATP and its hydrolysis reaction.
Analog compounds of ATP, such as GTP, uridine triphosphate, and cytidine triphosphate, also
store and transfer high-energy phosphate bonds but not to the extent of ATP. High-energy
phosphate compounds produced during metabolism, such as PEP and 1,3-biphosphoglycer-
ate, transfer their phosphate group into ATP. Energy stored in ATP is later transferred to lower
energy phosphate compounds such as glucose-6-phosphate and glycerol-3-phosphate, as
depicted in
Fig. 10.18
.
-60
Phosphoenolpyruvate
1,3-biphosphoglycerate
-50
~ P
~ P
-40
AT P
-30
~ P
~ P
-20
Glucose 6-phosphate
Glycerol 3-phosphate
-10
0
FIGURE 10.18
Transfer of biological energy from high-energy to low-energy compounds via ATP.
Search WWH ::
Custom Search