Biology Reference
In-Depth Information
Chapter 10
Unfolding the Future
Suzanne P. Jarvis and Anika S. Mostaert
UCD Conway Institute of Biomolecular and Biomedical Research,
University College Dublin, Dublin 4, Ireland
suzi.jarvis@ucd.ie; anika.mostaert@ucd.ie
In this chapter we bring together the findings of the previous
chapters into an overview of the emerging field of functional
amyloid, its hurdles and its potential, as it develops from discovery
to understanding and application.
10.1
The Field to Date
The previous chapters have provided an overview of the emerging
field of functional amyloid from its inception in 2000 with the
identification of physiological amyloid in fungi
1,2
(Chapter 3)
and silkworms
(Chapter 4). This was shortly followed in 2002
by a similar discovery in bacterial biofilms
3
4
(Chapter 7). In 2006,
specific mechanical functionality was identified and explained
relative to the molecular structure of the generic amyloid fibril
form found in natural adhesives
5
(Chapter 8) and in the same year
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