Biomedical Engineering Reference
In-Depth Information
Chapter 4
Further Developments in PET Motion
Correction
We have discussed methods for PET motion estimation and motion correction in
the previous chapters. In particular, a priori knowledge about the image generation
process, in terms of mass-preservation, was utilized to improve the motion estimates
needed for the advanced correction pipelines. This chapter gives an outlook of
potential improvements and modifications of the presented methods and future
advances of PET motion correction in general. The proposed improvements of the
process of motion estimation and motion correction are given by, e.g., extracting
motion from accompanying MRI scans instead of the PET data itself. Further,
we briefly discuss future developments of PET motion correction in clinical
applications.
4.1
Future Work of V
AMPIRE
and MPOF
The methods described in Chaps.
2
and
3
describe the general proceeding for mass-
preserving motion estimation and motion correction in PET. In the following,
we discuss some potential improvements of the described proceeding. These
modifications are:
Using an improved gating technique,
Extension to a spatial-temporal approach,
Application to dynamic PET data.
Further improvements by parameter optimization is not discussed in great detail.
We just provide the following list of starting points. It is desirable to determine the
Optimal number of respiratory and cardiac gates (cf. Sect.
3.2.3
),
Optimal regularization parameters (cf. Sects.
2.1.2
and
2.2.3
),
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