Resistance to Late Blight in Potato - Translational Genomics for Crop Breeding: Biotic Stress - page 233

genes detected. Among genes involved in various
resistances, some must play a role in interactions
with P. infestans . Homologs highly related to the
late blight resistance genes R1, RB, R2, R3a, Rpi-
blb2, and Rpi-vnt1.1 were present in the assem-
bly (Potato Genome Sequencing Consortium
2011). A more detailed study of the same genome
revealed 438 NB-LRR genes organized within 63
clusters. Among them there were 107 genes with
CC domain and 77 containing TIR domain (Jupe
et al. 2012). Significant sequencing efforts have
been devoted to another potato genome, RH89-
039-16 ( S. tuberosum ssp. tuberosum ), where
738 partial and full-length NB-LRR sequences
have been identified (Bakker et al. 2011). The
number of known functional Rpi genes and their
homologues identified by allele mining in var-
ious wild species is fast growing. Recently, an
online tool for cataloguing and analyzing the
R genes from Solanum section Petota in rela-
tion to their phylogeny, has been developed
(Vleeshouwers et al. 2011b, http://www.plant
breeding.wur.nl/SolRgenes/index.php).
On the other hand, the corresponding arse-
nal of P. infestans was predicted to contain 563
RXLR effectors, located in fast mutating, gene
sparse, and repeat rich regions of the genome
(Haas et al. 2009). Access to genome sequences
of both host and pathogen will, one hopes, bring
a better understanding of their interaction and
with that knowledge, progress in the application
of genomics in potato breeding.

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