Synthetic Morphogens and Pro-morphogens for Aided Tissue Regeneration - Biologically Responsive Biomaterials for Tissue Engineering - page 54

Table 3.2 Adhesion peptide sequences used in biomimetic materials (adapted from Pollock and Healy, 2009) [ 52 ]
Sequence Analogue protein Targeted cell receptor Reference

RGD(X) (and di-cysteine cyclic forms) Collagen (X = T), fibronectin (X = S),

vitronectin (X = V), laminin
(X = N), thrombospondin,
osteopontin, bone sialoprotein

a v b 3, a 5 b 1, a 3 b1 and other integrins Hern and Hubbell [ 53 ] , Schense

and Hubbell [ 54 ] , Shin et al.
[ 55 ] , Harbers and Healy [ 56 ] ,
Brandley and Schnaar [ 57 ]

DVDVPDGRGDLAYG Osteopontin a 5 b1 integrin Shin et al. [ 58 ]

CGGNGEPRGDTYRAY Bone sialoprotein av and b1 integrins Harbers and Healy [ 56 ]

FHRRIKA Bone sialoprotein Transmembrane proteoglycans Rezania and Healy [ 59 ]

DGEA Collagen-I a 2 b 1 Integrin Schense and Hubbell [ 54 ]

IKVAV Laminin- a a 1 b1 and a 3 b1 Integrins Silva et al. [60 ]

YIGSR Laminin- b-1 110 and 67 kDa Laminin-binding protein Schense et al. [ 61 ]