Biomedical Engineering Reference
In-Depth Information
adopted to explain within the proposed framework the feasibility of such an endeavor.
Numerical results support the adopted models, even if it is true that statistical verifications
require the laws of large numbers, and in the present case only a limited number of
measurements were carried out. However, the results of a limited number of measurements
provide a fairly good idea of the observed phenomena as it is well established by the theory
of statistical sampling. The present work is a first step in a direction of research that can be
very fruitful in the study of phenomena in the nano-size range since it illustrates the
possibility of performing nanoscale measurements with the usual procedures of optical
microscopy. Until now performing these measurements with such tremendous accuracy was
considered impossible.
Many of the derivations included in the chapter are similar to those included in classical
holography and holographic interferometry. The only difference with classic holography is
that the observations are made beyond the limits of diffraction-limited optical systems, thus
opening a whole new world of applications. This will prove very useful in the field of
biological sciences where super-resolution is of considerable value. At the present time,
there are problems in viewing biological materials with the utilization of electromagnetic
radiations of shorter wavelength particularly if in vivo is desired. This restriction has now
been removed due to the discoveries made and presented in this chapter.
References
[1] G.W. Stroke, D.G. Falconer, Attainment of high resolutions in wavefront-reconstruction imaging,
Phys. Lett. 13 (1964) 306
309.
[2] G.W. Stroke, Lensless Fourier-transform method for optical holography, Appl. Phys. Lett. 6 (1965)
201
203.
[3] D. Gabor, G.W. Stroke, R. Restrick, A. Funkhouser, D. Brumm, Optical image synthesis (complex
amplitude addition and subtraction) by holographic Fourier transformation, Phys. Lett. 18 (1965)
116
118.
[4] G.W. Stroke, An Introduction to Coherent Optics and Holography, second ed., Academic Press,
New York, 1969. 978-0126739565.
[5] M. Gustafsson, M. Sebesta, B. Bengtsson, S.G. Pettersson, P. Egelberg, T. Lenart, High-resolution digital
transmission microscopy—a Fourier holography approach, Opt. Lasers Eng. 41 (2004) 553
563.
[6] L. Granero, V. Mic
´
, Z. Zalevsky, J. Garc
´
a, Superresolution imaging method using phase shifting digital
lensless Fourier holography, Opt. Express 17 (2009) 15008
15022.
[7] I. McNulty, J. Kirz, C. Jacobsen, E.H. Anderson, M.R. Howells, D.P. Kern, High-resolution imaging by
Fourier transform x-ray holography, Science 256 (1992) 1009
1012.
[8] P. Thibault, M. Dierolf, A. Menzel, O. Bunk, C. David, F. Pfeiffer, High-resolution scanning X-ray
diffraction microscopy, Science 321 (2008) 379
382.
[9] G. Toraldo di Francia, La Diffrazione della Luce, Edizioni Scientifiche Einaudi, Torino, Italy, 1958
(In Italian).
[10] C.A. Sciammarella, Experimental mechanics at the nanometric level, Strain 44 (2008) 3
19.
[11] J.D. Jackson, Classical Electrodynamics, third ed., Wiley, New York, 2001. 978-0471309321.
[12] General Stress Optics Inc., Holo-Moir´ Strain Analyzer Version 2.0, Chicago.
,
http://www.stressoptics.
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