Melt-Derived Bioactive Glass - Bio-Glasses: An Introduction - page 26

been incorporated in a composite of collagen, Bioglass and tricalcium
phosphate bone void filler called Vitoss-BA ® (Orthovita, USA), which
shows higher new bone strength at 12-52 weeks after implantation
compared to the Bioglass-free material. Orthofix (Texas, USA) have
also developed a composite bone void filler called Origen ® made from
Bioglass, demineralised bone matrix (DBM) and gelatin.
Fine particles of Bioglass much smaller than those used in a bone
graft are now incorporated in toothpaste as the product NovaMin, as
described earlier [26]. The fine particulate cannot be detected by the
user but also increases the surface area and hence solubility, which is
necessary as the glass particles are not present in the saliva for long and
they need to dissolve and raise pH to mineralise dentine tubules and
reduce sensitivity. The toothpaste has low water content and is based
on poly(ethylene glycol) (PEG) and glycerol to minimise the reactivity of
the glass in the tube.
Patents have been filed in other areas such as using bioactive glasses
in a range of personal care products (Schott) and in hair straightening
formulations (L'Oreal).
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