Biomedical Engineering Reference
In-Depth Information
Table 9.4
Mechanical properties of several porous bioactive-glass-containing
composite scaffolds.
Elastic modulus
Compressive strength
(MPa)
(MPa)
PDLLA, porosity 93% (via TIPS)
0.9
0.08
Filled with 30 wt% Bioglass
1.2
0.08
PLGA (75LA : 25GA), porosity 93%
(via TIPS)
0.4
0.04
Filled with 30 wt% Bioglass
0.8
0.10
PLGA (50LA : 50GA), porosity 31%
(microsphere sintering)
26
0.53
Bioglass filled, porosity 43%
(microsphere sintering)
51
0.42
PLLA, porosity 80% (via phase
separation)
107
-
PDLLA/25 wt% Bioactive glass
(porosity 77%)
145
-
PDLLA/50 wt% Bioactive glass
(porosity 78%)
179
-
lay down material layer by layer and form a construct. SFF methods
thereby provide enhanced control over scaffold shape, material, porosity
and pore architecture, including size, geometry, orientation, branching
and pore interconnectivity. However, at present, most SFF materials are
3D grid-like systems rather than exact replicas of tissue architecture
(Figure 9.7). Although the scaffolds are less aesthetically pleasing than
Figure 9.7
A Bioglass-polycaprolactone composite made by an extrusion-based
SFF process.
