Biomedical Engineering Reference
In-Depth Information
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Y-Y1 receptors by antisense oligodeoxynucleotides. Science , 259 , 528-531.
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and angiotensinogen mRNA in the brain of spontaneously hypertensive rats reduces hypertension
of neurogenic origin. Regulatory Peptides , 49 , 167-174.
10. Kimura, B., Mohuczy, D., Tang, X. and Phillips, M.I. (2001) Attenuation of hypertension and
heart hypertrophy by adeno-associated virus delivering angiotensinogen antisense. Hypertension ,
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double-stranded RNA in Caenorhabditis elegans . Nature , 391 , 806-811. Andrew Fire and Craig
Mello Nobel prize 2006.
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small interfering RNA lowers high blood pressure and improves cardiac function in myocardial
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encodes small RNAs with antisense complementarity to lin-14. Cell , 75 , 843-854.
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1-728. Useful collection of gene therapy methods.
25. Wu, P., Phillips, M.I., Bui, J. and Terwilliger, E.F. (1998) Adeno-associated virus vector-mediated
transgene integration into neurons and other nondividing cell targets. Journal of Virology , 72 ,
5919-5926. Addresses the question of integration of AAV.
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