Biology Reference
In-Depth Information
induced in human arterial smooth muscle cells of the synthetic, proliferative phenotype. J Clin
Invest 100:2611-2621
Rybalkin SD, Rybalkina I, Beavo JA, Bornfeldt KE (2002) Cyclic nucleotide phosphodiesterase
1C promotes human arterial smooth muscle cell proliferation. Circ Res 90:151-157
Sartorius CA, Tung L, Takimoto GS, Horwitz KB (1993) Antagonist-occupied human progester-
one receptors bound to DNA are functionally switched to transcriptional agonists by cAMP.
J Biol Chem 268:9262-9266
Sastry BK, Narasimhan C, Reddy NK, Anand B, Prakash GS, Raju PR, Kumar DN (2002) A study
of clinical efficacy of sildenafil in patients with primary pulmonary hypertension. Indian Heart
J 54:410-414
Sastry BK, Narasimhan C, Reddy NK, Raju BS (2004) Clinical efficacy of sildenafil in primary
pulmonary hypertension: a randomized, placebo-controlled, double-blind, crossover study.
J Am Coll Cardiol 43:1149-1153
Schacke H, Docke WD, Asadullah K (2002) Mechanisms involved in the side effects of gluco-
corticoids. Pharmacol Ther 96:23-43
Schermuly RT, Pullamsetti SS, Kwapiszewska G, Dumitrascu R, Tian X, Weissmann N,
Ghofrani HA, Kaulen C, Dunkern T, Schudt C, Voswinckel R, Zhou J, Samidurai A,
Klepetko W, Paddenberg R, Kummer W, Seeger W, Grimminger F (2007) Phosphodiesterase
1 upregulation in pulmonary arterial hypertension: target for reverse-remodeling therapy.
Circulation 115:2331-2339
Schudt C, Tenor H, Hatzelmann A (1995) PDE isoenzymes as targets for anti-asthma drugs. Eur
Respir J 8:1179-1183
Secchiero P, Zella D, Curreli S, Mirandola P, Capitani S, Gallo RC, Zauli G (2000) Pivotal role of
cyclic nucleoside phosphodiesterase 4 in Tat-mediated CD4
+
T cell hyperactivation and HIV
type 1 replication. Proc Natl Acad Sci USA 97:14620-14625
Seldon PM, Barnes PJ, Meja K, Giembycz MA (1995) Suppression of lipopolysaccharide-induced
tumor necrosis factor-
a
generation from human peripheral blood monocytes by inhibitors
of phosphodiesterase 4: interaction with stimulants of adenylyl cyclase. Mol Pharmacol 48:
747-757
Selige J, Tenor H, Hatzelmann A, Dunkern T (2010) Cytokine-dependent balance of mitogenic
effects in primary human lung fibroblasts related to cyclic AMP signaling and phosphodiester-
ase 4 inhibition. J Cell Physiol 223:317-326
Shrewsbury S, Pyke S, Britton M (2000) Meta-analysis of increased dose of inhaled steroid or
addition of salmeterol in symptomatic asthma (MIASMA). BMJ 320:1368-1373
Sindi A, Todd DC, Nair P (2009) Antiinflammatory effects of long-acting
b
2
-agonists in patients
with asthma: a systematic review and meta-analysis. Chest 136:145-154
Singh D, Petavy F, Macdonald AJ, Lazaar AL, OC BJ (2010) The inhaled phosphodiesterase
4 inhibitor GSK256066 reduces allergen challenge responses in asthma. Respir Res 11:26
Smith SJ, Brookes-Fazakerley S, Donnelly LE, Barnes PJ, Barnette MS, Giembycz MA (2003)
Ubiquitous expression of phosphodiesterase 7A in human proinflammatory and immune cells.
Am J Physiol Lung Cell Mol Physiol 284:L279-L289
Smith SJ, Cieslinski LB, Newton R, Donnelly LE, Fenwick PS, Nicholson AG, Barnes PJ,
Barnette MS, Giembycz MA (2004) Discovery of BRL 50481 [3-(N, N-dimethylsulfo-
namido)-4-methylnitrobenzene), a selective inhibitor of phosphodiesterase 7: In vitro studies
in human monocytes,
lung macrophage and CD8+ T-lymphocytes. Mol Pharmacol 66:
1679-1689
Snyder PB, Beaton G, Rueter JK, Fanning DL, Warren SD, Hadidaruah SS (2002) Selective
PDE3B inhibitors and uses of the same in therapy. ICOS Corporation, WO02/070469 A2
Souness JE, Villamil ME, Scott LC, Tomkinson A, Giembycz MA, Raeburn D (1994) Possible
role of cyclic AMP phosphodiesterases in the actions of ibudilast on eosinophil thromboxane
generation and airways smooth muscle tone. Br J Pharmacol 111:1081-1088
Souness JE, Aldous D, Sargent C (2000) Immunosuppressive and anti-inflammatory effects of
cyclic AMP phosphodiesterase (PDE) type 4 inhibitors. Immunopharmacology 47:127-162
