Biomedical Engineering Reference
In-Depth Information
Figure 1 . ( a ) Morphometric segmentation of T 1 -weighted MRI data in coronal sections using the
morphometric methodology of the Center for Morphometrc Analysis (54,91). a-d are four representa-
tive coronal sections of the human brain in the rostral-caudal dimension showing limbic and paralim-
bic structures. The colored sphere shows the color coding scheme applied for the visualization of the
tensors: red stands for the medial-lateral orientation, green indicates the anterior-posterior orientation,
and blue shows the superior-inferior orientation. Abbreviations: FOC = Frontal Orbital Cortex, FMC =
Frontal Medial Cortex, CGa = Cingulate Gyrus (anterior), CGp = Cingulate Gyrus (posterior), NAc =
Nucleus Accumbens, TP = Temporal Pole, INS = Insula, BF/SLEA = Basal Forebrain/Sublenticular
Extended Amygdala, Hip = Hippocampus, PH = Parahippocampal Gyrus, VT = Ventral Tegmental
Area, Tha = Thalamus, Hyp = Hypothalamus, BS = Brain Stem, Amy = Amygdala. ( b ) Diffusion
tensor magnetic resonance (DT-MR) image of limbic fiber pathways. (b) shows the primary eigenvec-
tor map (PEM) of a coronal slice at the level of the anterior commissure; the T 2 -EPI image of this slice
is shown in (a). Dotted rectangles highlight regions that include major limbic pathways such as the
fornix, cingulum bundle, medial forebrain bundle and ventral amygdalofugal projection (in the basal
forebrain or BF). Abbreviations: CB = cingulum bundle, UF = uncinate fasciculus, ac = anterior com-
missure, CC = corpus callosum, lv = lateral ventricle. For further details on DT-MRI, please see Ma-
kris et al. (157,159).
neural integrity, fMRI is likely to become a technique more commonly used for
researching neuropsychiatric illness, and potentially clinical diagnoses. What
Search WWH ::




Custom Search