Biomedical Engineering Reference
In-Depth Information
Figure 16 . Corrosion cast of hamster eye vascular network (bar = 50 m) (86).
Figure 17 . Three-dimensional regeneration of glomerulus capillary structure (1).
walls, into cells. Transport of molecules may also be affected by electrostatic
interactions between the molecules and the extracellular matrix. To fully under-
stand the transport of molecules in any system, the effects and interplay of these
three factors in transport must be understood.
Analysis of molecular transport in physiological systems must include the
effect of interactions between the molecules and cells. A simple case of nutrient
transport by diffusion in the presence of cells can be modeled by considering
each cell to be a point sink, and including a term for these point sink in the dif-
fusion equation. In one dimension, the concentration of nutrient L ( x ) is de-
scribed by:
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