Biomedical Engineering Reference
In-Depth Information
Figure 5
. Size-selective movement of submicron beads based on the balance of electrothermal force
and DEP. Reprinted with permission from Green and Morgan (7).
Figure 6
. (
A
) Images representing the microscale separation of
B. globigii
spores and heat-killed
E.
coli
bacteria on the 5 + 5 array. The electrodes in the array were addressed with an AC voltage at 50
kHz and 5 V (p-p). The spores and bacteria were suspended in a 280-mM mannitol solution having a
conductivity of 20
S/cm. (
B
) Expanded view showing that the spores were collected on the elec-
trodes and the bacteria were repelled from the electrodes. Reprinted with permission from Huang et
al. (9).
the microchannel surface. Therefore, cancerous and noncancerous cells can be
separated and identified based on their electrical properties. This separation
technique is known as flow field fractionation (FFF). A schematic of this separa-
tion technique is shown in Figure 4 (taken from (5)).
The combination of DEP with electrothermal flow and AC electroosmosis
is discussed in detail by Green et al. (7), who demonstrated how, in the absence
