Biomedical Engineering Reference
In-Depth Information
D
Maintain constant contact
If social quarantine rules prevent contact with an infected
source
Host
, this user-specified option forces the target
Host
to seek another source
Host
for interaction.
Reproductive ages (user-specified number of parturitions at integer
Host
ages randomly selected from a uniform distribution with
user-specified minimum and maximum. Call the
Reproduce
opera-
tion below when current age = one of the reproductive ages)
Inflammatory response
D
Factor modifying initialized host resistance parameter such that
realized resistance = CDF
1
Normal
[Inverse CDF
2
Normal
(initialized resis-
tance) + Inverse CDF
2
Normal
(inflammatory factor)], with inflamma-
tory factor being a
Host
-specific constant that is either initialized
at a user-specified constant or transmitted with noise from the
parent as described below in
Reproduce
D
Costly in that natural lifespan decreases the square root of the
inflammatory response parameter, such that realized natural
lifespan = initialized natural lifespan (1/inflammatory re-
sponse factor squared)
Sickness behavior sensitivity parameter
D
Factor modifying the initialized sickness behavior sensitivity
parameter such that the realized probability of avoiding social
contact when sick = initialized contact probability rule result
∗
sickness behavior sensitivity parameter
inflammatory factor,
with sickness behavior sensitivity being a
Host
-specific con-
stant that is transmitted with noise from the parental Host as
described below in
Reproduce
∗
Natural lifespan (health status becomes dead when age >= this
value; initialized for each
Host
as a random integer from a normal
distribution with user-specified mean and standard deviation, and
potentially modified by the inflammatory response parameter
above)
Operations
Age 1 Time Unit
D
If health status of this
Host
is not dead, then
Increase current age by 1
Update
Host
resistance based on number of contacts real-
ized at time
t
- 1
Survey this
Host's
resident
Pathogen
objects'
Progress
Disease
operator to update
Host's
current health status
