Biomedical Engineering Reference
In-Depth Information
Operations
Initialize Epidemic
D Create the designated number of
Host
objects
D Allocate potential linkages to each
Host
according to a user-
specified rule
Random (each
Host
is targeted by N randomly selected
source agents, where N is a user-specified integer)
Reciprocal (all contact links are bidirectional)
Small-world (
Hosts
are randomly assigned varying num-
bers of links according to a power law as described (5,6),
such that small numbers of
Hosts
are highly connected
and most hosts are sparsely connected. User specifies the
distribution in terms of the total number of links in the
contact network.)
Block (user-specified groups of N
Hosts
all share recipro-
cal linkage)
Block +1 (as above, with one member of each block also
reciprocally linked to the next adjacent block)
Band (each
Host
is linked to a user-specified N socially
adjacent Hosts)
Superimposed combinations of the options above
D Allocate infections to a user-specified number of
Hosts
D Allocate all other user-specified
Host
characteristics (each de-
tailed in
Host
below)
Natural lifespan
Reproduction age
Contact realization rules
Host
resistance to infection
Host
resistance dynamics rule
Run Epidemic
D For the number of time units specified by duration of simula-
tion, execute the
Age 1 Time Unit
operation for each
Host
(de-
scribed below)
D Update the realized host population and health status trajecto-
ries after each time
Summarize Course
D
Provide the final trajectory of realized
Host
population size,
realized
Host
health status frequencies, and final
Host
popula-
tion status