Biomedical Engineering Reference
In-Depth Information
epidemic and summarizes the results, (b) an
Epidemic
object representing the
realized course of a single epidemic, (c) a
Host
object that interacts with other
Hosts as part of a disease transmission network, and (d) a
Pathogen
object that
can be transmitted among Hosts and interacts with the Host to modify its health
status. The basic properties and operations of each object are summarized be-
low:
Object: SimulationSystem
Properties
Number of simulations (user input integer)
Operations
Run Simulation
D
For each simulation cycle, create and initialize an
Epidemic
object (described below)
D
Collect results on host health status as
Epidemic
iterates over
time (described below)
Plot Results
for each simulation (from the
Epidemic
's
Summarize
Course
operation below) and compute summary statistics across
the ensemble of simulations
D
Mean fraction of
Host
population uninfected, infected, visibly
sick, and dead at each timepoint
D
Mean fraction of
Host
population alive at end of simulation
D
Mean time to
Host
population extinction
D
Mean time to
Pathogen
population extinction
D
Peak prevalence of infection over time
D
Median time of peak infection prevalence
Object: Epidemic
Properties
Duration of simulation (user input integer time units)
Initial number of
Hosts
infected (user input integer)
Realized
Host
population trajectory (
Hosts
alive at each time
unit—product of the
Run Epidemic
operation below)
Realized
Host
health status trajectory (number and percentage un-
infected, latently infected, visibly infected, and dead at each time
point—product of the
Run Epidemic
operation below)
Final
Host
population status (population survives or perishes
within duration of simulation—product of the
Run Epidemic
opera-
tion below)
