Biomedical Engineering Reference
In-Depth Information
6. Elowitz MB, Levine AJ, Siggia ED, Swain PS. 2002. Stochastic gene expression in a single
cell.
Science
297
:1183-1186.
7. Endy D, Yu L, Yin J, Molineaux IJ. 2000. Computation, prediction, and experimental tests of
fitness for bacteriophage T7 mutants with permuted genomes.
Proc Natl Acad Sci USA
97
:5375-5380.
8. Garfinkel D. 1968. The role of computer simulation in biochemistry.
Comp Biomed Res
2
(1):31.
9. Garfinkel D. 1980. Computer modeling complex biological systems and their simplifications.
Am J Phys
239
(1):R1.
10. Garfinkel D. 1985. Computer-based modeling of biological systems which are inherently com-
plex: problems, strategies and methods.
Biomed Biochim Acta
44
(6):823.
11. Gatenby RA, Maini PK. 2003. Cancer summed up.
Nature
421
:321.
12. Hasty J, McMillen D, Collins JJ. 2002. Engineered gene circuits.
Nature
420:224-230.
13. Hasty J, McMillen D, Isaacs F, Collins JJ. 2001. Computational studies of gene regulatory
networks:
in numero
molecular biology.
Nature Rev Genet
2
:268-279.
14. Heinrich R, Rapoport SM. 1977. Metabolic regulation and mathematical models.
Prog Biophys
Mol Biol
32
:1.
15. Hucka M, Finney A, Sauro HM, Bolouri H, Doyle JC, Kitano H, Arkin AP, Bornstein BJ, Bray
D, Cornish-Bowden A, Cuellar AA, Dronov S, Gilles ED, Ginkel M, Igor V, Goryanin I, Hed-
ley WJ, Hodgman TC, Hofmeyr J-H, Hunter PJ, Juty NS, Kasberger JL, Kremling A, Kummer
U, Le Novere N, Loew LM, Lucio D, Mendes P, Mjolsness ED, Nakayama Y, Nelson MR,
Nielsen PF, Sakurada T, Schaff JC, Shapiro BE, Shimizu TS, Spence HD, Stelling J, Takahashi
K, Tomita M, Wagner J, Wang J. 2003. The systems biology markup language (SBML): a me-
dium for representation and exchange of biochemical network models.
Bioinformatics
19
(4):524-531.
16. Ideker T, Galitski T, Hood L. 2001. A new approach to decoding life: systems biology.
Annu
Rev Genomics Hum Genetics
2
:343-372.
17. Kitano H. 2002. Computational systems biology.
Nature
420
:206-210.
18. Kitano H. 2002. Systems biology: a brief overview.
Science
295
:1662-1664.
19. Lockhart DJ, Winzeler EA. 2000. Genomics, gene expression and DNA arrays.
Nature
405
:827-836.
20. McAdams HM, Arkin A. 1998. Simulation of prokaryotic genetic circuits.
Annu Rev Biophys
Biomol Struct
27
:199-224.
21. McAdams HM, Arkin A. 1999. It's a noisy business! Genetic regulation at the nanomolar scale.
Trends Genet
15
(2):65-69.
22. Mesarovic MD. 1968. Systems theory and biology: view of a theoretician. In
Systems theory in
biology
, pp. 59-87. Ed. MD Mesarovic. Springer, New York.
23. Rao CV, Wolf DM, Arkin AP. 2002. Control, exploitation and tolerance of intracellular noise.
Nature
420
:231-237.
24. Rosen R. 1978.
Fundamentals of measurement and representation of natural systems
. North-
Holland, New York.
25. Savageau MA. 1969a. Biochemical system analysis. I. Some mathematical properties of the
rate law for the component enzymatic reactions.
J Theor Biol
25
:365.
26. Savageau MA. 1969b. Biochemical system analysis. II. The steady-state solutions for an
n
-
pool system using a power law approximation.
J Theor Biol
25
:370.
27. Savageau MA. 1976.
Biochemical systems analysis
. A study of function and design in molecu-
lar biology. Addison-Wesley, Reading, MA.
28.
Schuster S, Dandekar T, Fell DA. 1999. Detection of elementary flux modes in biochemical
networks: a promising tool for pathway analysis and metabolic engineering.
Trends Biotechnol
18
:326-332.
