Biomedical Engineering Reference
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Figure 2 . The clustering coefficient C offers a measure of the degree of interconnectivity
in the neighborhood of a node. For example, the red node whose neighbors are all con-
nected to each other has C = 1 (left), whereas the red node with no links between its
neighbors has C = 0 (right).
the neighbors of a particular node are connected to each other (Figure 2). For
example, in a friendship network C reflects the degree to which friends of a par-
ticular person are friends with each other as well. Formally, the clustering coef-
ficient of node i is defined as
2
n
C
=
,
i
[2]
i
kk
(
)
i
i
where n i denotes the number of links connecting the k i neighbors of node i to
each other. Accordingly, we can define the average clustering coefficient as
1
N
= .
C
C
[3]
i
N
i
=
1
An additional important measure of the network's structure is the function C ( k ),
defined as the average clustering coefficient of all nodes with k links. If C ( k ) is
independent of k , the network is either homogeneous or it is dominated by nu-
merous small tightly linked clusters. In contrast, if C ( k ) follows C ( k ) ~ k -1 , the
network has a hierarchical architecture, meaning that sparsely connected nodes
are part of highly clustered areas (12,27,46,47). In such hierarchical networks
communication between the different highly clustered neighborhoods is main-
tained by a few hubs.
As we will see below, the degree distribution P ( k ) and the k dependence of
C ( k ) can have generic features, allowing us to classify various networks. Pa-
rameters such as the average degree < k >, average path length < l >, and average
clustering coefficient < C > characterize the unique properties of the particular
network under consideration, and therefore are less generic.
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